Two years after the events of the first film, Deadpool/Wade Wilson has become a mercenary who works worldwide, killing various criminals. Following an aborted attempt on the life of the head of a drug cartel operating in his home city, Deadpool returns home to his girlfriend Vanessa Carlysle to celebrate their anniversary. Deadpool gifts Vanessa a skee-ball token, in reference to their first date, and the two agree to start a family. Later that night the drug lord attacks Wade at his home and, in the process, Vanessa dies. Wade chases the criminal through the streets and embraces him on the road as a truck runs into them and kills the drug lord. Six weeks later Deadpool decides to kill himself by blowing up his apartment with several barrels of high-grade fuel. During his 'death', Wade has a vision of Vanessa in the afterlife; she says that his heart is not the right place yet, leaving Wade confused. Colossus arrives at the now-destroyed apartment and brings a dismembered Wade back to the Xavier Mansion in an attempt to recruit Deadpool into the X-Men and help him get through his grief. Deadpool eventually agrees to join the X-Men and, together with Colossus and Negasonic Teenage Warhead , responds to a situation involving a young mutant named Russell Collins , who calls himself Firefist, being able to produce extremely high temperatures from his fists that can ignite nearby objects. After several failed attempts to calm down Russell, Wade discovers that the headmaster and staff of the orphanage have abused him, physically, and ends up shooting one of the staff; this leads to both Deadpool's and Russell's arrest, whereupon they are restrained with collars that negate their mutant powers, including Deadpool's healing factor which means Deadpool's cancer begins to briskly kill him.